Understanding Active Pharmaceutical Ingredients

Understanding Active Pharmaceutical Ingredients

Have you ever wondered how pharmaceutical drugs work? The ingredients in a pharmaceutical drug are responsible for the physiological reaction your body has to the medication. Many components are involved in the development of pharmaceuticals, but active pharmaceutical ingredients are the ingredients that produce the intended effects of the drug an individual is taking.    

Understanding Active Pharmaceutical Ingredients   

Active Pharmaceutical Ingredients (API) refer to the biologically active components of a drug. An API is the primary ingredient used in a pharmaceutical drug, paired with secondary components known as excipients. Excipients are the inactive substances that serve as vehicles for the API.     

The Manufacturing Process of Active Pharmaceutical Ingredients   

The manufacturing of an API is a multistep process completed by pharmaceutical manufacturing companies and API- specific manufacturers. It’s easy confuse the API and raw materials in the manufacturing of a pharmaceutical drug. The raw materials refer to chemical compounds—called intermediates in this process—that are used as bases to make an API. Several chemical compounds are often needed to create an API, which passes through multiple kinds of compounds or intermediates when they’re changing from raw materials into the API.  

After this long process, the API goes through the purification, crystallization, drying, milling, and packaging processes.

An Example of an API   

Understanding active pharmaceutical ingredients is easy when you’re presented with an example. One example of an API is acetylsalicylic acid, which is the API in aspirin. This ingredient is the active ingredient that will fight the pain of your fever, headache, or aches and pains. The excipients of aspirin are those that make up the vessel of the drug, such as the maize and starch that create the pill.   

Moravek is a trusted provider of carbon-14 API radiolabeling services for use in clinical trials during the pharmaceutical manufacturing process.