In the United States, an estimated 810,000 people work in chemical production fields, including the pharmaceutical sector. In this industry, C14 radiolabeling remains the standard and is the first choice for the labeling of active pharmaceutical ingredients. This type of labeling is crucial for API GMPs, as it permits more information to be collected pertaining to metabolism, distribution, adsorption, and excretion — all of which can be critical to understanding the pharmaceutical during the clinical study stages.
It’s important to note that, in recent years, APIs (along with their delivery methods) have increased in complexity as research has progressed and unearthed new discoveries. This means that radiolabeling now contains new challenges, which has prompted new technologies to be employed to ensure process efficiency.
Fume hoods are an important part of any laboratory. Aiding in ventilation, these exhaust systems help remove harmful chemical fumes from the air (for instance, during radiolabeling or GMP synthesis) to better ensure the safety of scientists and personnel. Fume hoods are a crucial part of maintaining clean room standards and can prevent an excess amount of vapor, aerosol, gases, and dust from accumulating in the air.
The U.S. is the leading national producer of chemical products around the world. The vast majority of laboratories in the country use most of these chemicals. The types and amounts of chemicals used vary from lab to lab based on whether the lab focuses on compound production, research, basic acid digestion, and so on.
Our effectiveness in the field is largely thanks to our advanced machinery and thorough safety techniques. One piece of equipment, the fume hood, for example, has an important place in the pharmaceutical world. Continue reading to learn more about safe fume hood practices to ensure GMP quality control, the types of fume hoods, and when to use one.
Chemical purity is no joke. It requires extensive testing and all conditions must be met in order for a proper purity grade to be earned.
Chemical purity is best defined as an untouched and unmixed substance. A chemical or product must achieve this before it is sold on the shelves of drugstores across the nation. This rating deems that the medication or product is safe for human use.
While many industries require chemical purity, there are some that the average consumer might be more familiar with. Here is a quick look into the main chemical manufacturers that utilize this idea to deliver safe and effective products.