Storing Pharmaceuticals: Important Guidelines to Consider

Why are GMP Regulations Important in Today’s Pharmaceutical Labs?

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With the U.S. holding more than 45% of the global pharmaceutical market, it’s important for laboratories to abide by certain regulations. The regulations in place help to maintain pharmaceutical quality so they’re safe for consumers. Good Manufacturing Practice (GMP) regulations give pharmaceutical labs standards they need to meet to ensure their products are both safe and effective. So let’s take a closer look at why GMP regulations are so important in today’s pharmaceutical labs.

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C14 Radiolabeling: What You Need to Know

c14 radiolabelingCarbon is an element that has been used for a variety of scientific purposes over the years, like radiocarbon dating, which was developed around 1946 by Willard F. Libby. But in today’s pharmaceutical labs, carbon 14 plays a crucial role in drug development. And because of depleting supplies and increasing prices, carbon 14 production is at an all-time high. But what can carbon 14 be used for and how is it used safely? Let’s take a look at a few important things to know about C14 radiolabeling.

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What Exactly Is Radiolabeling?

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Radiolabeling is a process that is frequently used in medicine, drug research and development, and environmental case studies. Using this process, researchers can track the movement or breakdown of target molecules. For instance, drug researchers can see how a new drug is metabolized as it travels through the test subject’s body. To accomplish this, atoms within the target molecule are replaced by isotopes of the same atom.

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What Kind of Fume Hoods Are Available to Today’s Labs?

gmp standardsWhile there are a lot of essential pieces of equipment used in laboratories, fume hoods are one of the most important devices labs have. When lab technicians are working with materials that are classified with health hazards, it’s important to work in an area that has a fume hood so the harmful fumes can be removed safely from the area. A recent survey found that about one-fifth of laboratories were planning on replacing their fume hood, with one-third of them needing to be replaced due to old age. So if you’re in the market for a new fume hood, let’s take a look at some of the most common types of fume hoods.

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3 Benefits Cleanrooms Can Offer

carbon 14 production

 

With the United States being the number one largest national producer of chemical products in the world, it’s no surprise that there is an astounding number of laboratories throughout the country. And whether that laboratory is engaged in Carbon 14 production or pharmaceutical research and development, many laboratory settings contain cleanrooms. In labs, cleanrooms serve a very important purpose, and this article is going to take a closer look at the benefits cleanrooms can offer.

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Why is Temperature Monitoring Important in Labs?

gmp quality controlWhen it comes to handling sensitive items in laboratories, like radiolabeled compounds, it’s important to make sure they’re stored, worked with, and manufacturers in proper temperatures. Under proper GMP storage conditions, like in a cleanroom, compounds and chemicals can be manufactured and used correctly. Cleanrooms are an important part of any laboratory — compared to the ambient outdoor air in urban areas, which contain 35 million particles per cubic meter, cleanroom environments offer just 12 particles per cubic meter. This allows lab technicians to control the environment chemicals are used in. So let’s take a look at a few reasons why temperature monitoring in labs is important.

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How Do Chemical Manufacturers Assess Purity?

gmp storage conditionsTesting the purity of substances is one of the most important tasks chemical manufacturers are faced with. If an impure substance is used, it could cause adverse effects. For example, a 2012 fungal meningitis outbreak that caused the deaths of 48 people was traced back to a pharmacy that hadn’t been using proper cleaning and maintenance techniques. If the pharmacy had taken more time to use proper methods in the lab, including assessing the purity of the substances used in the drug that caused the outbreak and proper GMP storage conditions, the disaster could have been prevented. So, how do chemical manufacturers assess purity? Let’s take a look at a few common methods used in today’s labs.

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The Importance of Fume Hoods in Laboratory Settings

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Today’s technology makes laboratory settings safer and more effective than ever. From clean rooms to effectively removing fumes, scientists can do it all with technology. In fact, electronic sensing devices allow scientists to maintain and monitor the humidity in clean rooms as close as plus or minus 1%. But despite advances in technology, when it comes to working with hazardous materials, scientists still need to work in an area that has chemical fume hoods. Let’s take a closer look at why fume hoods are so important and some basic guidelines that should be followed.

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