What to Look for In Radiolabeling Services

In the United States, over 810,000 people are currently working in the chemical industry, including pharmaceuticals. If you are one of these individuals, then you understand how critical radiolabeled compounds can be to the testing process. Being able to track the metabolizing rate of drugs within the body is crucial for developing safe and effective drugs that could result in life saving discoveries. While many labs send samples off for radiolabeling, it’s important to know what to look for when it comes to selecting the right radiolabeling service for your needs.

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Reasons for Choosing Carbon-14 for Radiolabeling

c14 radiolabeling

Radiolabeling is a scientific technique used to track the passage of a molecule. The technique incorporates a radioisotope through a reaction, cell, organism, biological system, or metabolic pathway. The reactant is labeled by replacing specific atoms by their isotope.

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Understanding GMP Storage Condition Standards

Currently, the United States is responsible for 45% of the pharmaceutical market worldwide. With respect to this, GMP storage conditions are especially important in this industry. At a glance, GMP is a system that works to ensure that products are consistent and controlled with respect to quality standards. In the pharmaceutical industry, this helps minimize the risk of contamination and potentially dangerous mixups with products.

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Radiolabeled Compound Handling 101

The United States remains to be the leading producer of various chemicals associated with drugs, food additives, and preservatives. With this title come several challenges, such as accidents happening in various laboratories and chemical manufacturing plants. As a leader of a chemical producing plant, you already know the accidents associated with such chemicals, especially radiolabeled compounds.

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Good Manufacturing Practice — What Do These Guidelines Dictate?

gmp quality control

When you are creating pure, high quality radiolabeled compounds, you need to hold your production process to the absolute highest material and clean room standards possible. There is a reason Moravek was given two large grants by the National Institutes of Health — it is due to strict adherence to Good Manufacturing Practice, or GMP.

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Understanding Carbon-14 Use In Pharmaceutical Manufacturing

radiolabeled compounds

In the United States, an estimated 810,000 people work in chemical production fields, including the pharmaceutical sector. In this industry, C14 radiolabeling remains the standard and is the first choice for the labeling of active pharmaceutical ingredients. This type of labeling is crucial for API GMPs, as it permits more information to be collected pertaining to metabolism, distribution, adsorption, and excretion — all of which can be critical to understanding the pharmaceutical during the clinical study stages.

It’s important to note that, in recent years, APIs (along with their delivery methods) have increased in complexity as research has progressed and unearthed new discoveries. This means that radiolabeling now contains new challenges, which has prompted new technologies to be employed to ensure process efficiency.

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Fume Hoods: Proper Usage and Maintenance Tips

fume hoods

Fume hoods are an important part of any laboratory. Aiding in ventilation, these exhaust systems help remove harmful chemical fumes from the air (for instance, during radiolabeling or GMP synthesis) to better ensure the safety of scientists and personnel. Fume hoods are a crucial part of maintaining clean room standards and can prevent an excess amount of vapor, aerosol, gases, and dust from accumulating in the air.

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6 Safety Tips for the Handling and Storage of Radiolabeled Compounds

radiolabeled compounds

The U.S. is the leading national producer of chemical products around the world. The vast majority of laboratories in the country use most of these chemicals. The types and amounts of chemicals used vary from lab to lab based on whether the lab focuses on compound production, research, basic acid digestion, and so on.

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From Blush to Allergy Medications: Industries That Require Chemical Purity

Chemical purity is no joke. It requires extensive testing and all conditions must be met in order for a proper purity grade to be earned.

Chemical purity is best defined as an untouched and unmixed substance. A chemical or product must achieve this before it is sold on the shelves of drugstores across the nation. This rating deems that the medication or product is safe for human use.

While many industries require chemical purity, there are some that the average consumer might be more familiar with. Here is a quick look into the main chemical manufacturers that utilize this idea to deliver safe and effective products.

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