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Fume Hoods Explained: 4 Basic Types To Get You Started
Science is an expansive and constantly evolving field. As more discoveries are made, our understanding of the world we live in grows and develops in (occasionally) incomprehensible ways; we learn what benefits us, what harms us, and everything in between. Laboratories are often at the forefront of such revelations and are protected as such.
How To Store And Dispose Of Radiolabeled Compounds
Radiolabeled compounds are extremely useful in the modern medical industry, and extremely beneficial to society. From drug trials to cancer treatments, the synthesis of carbon 14 production (also known as 14C labeling) can save lives by allowing new drugs to become available nationally.
Radioisotope Storage: GMP Explained
Radiolabeled compounds rely on the use of radioactive isotopes (also referred to as radioisotopes) for enrichment. Since radiation is historically bad for human beings, extra care must be taken to ensure that no harm comes to either the people involved in developing these radiochemicals or the compounds themselves; after all, if improper handling procedures were common in...
Radiolabeling At Work: Treating Kidneys With Nanotechnology
Acute kidney injury (AKI), previously known as acute renal failure, kills around 1.7 million people every year. The kidneys produce a rapid buildup of nitrogenous wastes and also decrease urine output; severe complications -- including muscle weakness, paralysis, and heart rhythm problems -- ensue.
Good Manufacturing Practices As Stated By The RDRC And FDA
The U.S. has long been a driver of scientific discovery. From cures to vaccines, medical implementation of these advances has been at the forefront of our nation's goals. The finding of radiolabeling applications is one such breakthrough. Radiolabeling (and isotopic labeling) is valuable to the developments of other breakthroughs: C14 radiolabeling (also known as 14C labeling)...
Clinical Trials: Taking A Look At The Phases Involved
Getting a new drug off the ground takes a lot of work. You have to follow stringent (and very specific) FDA guidelines, exercise top-tier clean room standards (and GMP standards) to prevent contamination and reduce risk, and perform dozens of radiolabeled tests to ensure the drug is going to the right target within the human...
Storing Pharmaceuticals: Important Guidelines to Consider
When it comes to pharmaceuticals, proper storage is absolutely essential. Guidelines and regulations for GMP storage conditions are in place because even if a product is manufactured properly, something can go wrong if the product is stored improperly. So let's explore a few basic guidelines to keep in mind when storing pharmaceuticals.
Why are GMP Regulations Important in Today's Pharmaceutical Labs?
With the U.S. holding more than 45% of the global pharmaceutical market, it's important for laboratories to abide by certain regulations. The regulations in place help to maintain pharmaceutical quality so they're safe for consumers. Good Manufacturing Practice (GMP) regulations give pharmaceutical labs standards they need to meet to ensure their products are both...
C14 Radiolabeling: What You Need to Know
Carbon is an element that has been used for a variety of scientific purposes over the years, like radiocarbon dating, which was developed around 1946 by Willard F. Libby. But in today's pharmaceutical labs, carbon 14 plays a crucial role in drug development. And because of depleting supplies and increasing prices, carbon 14 production is...
What Exactly Is Radiolabeling?
Radiolabeling is a process that is frequently used in medicine, drug research and development, and environmental case studies. Using this process, researchers can track the movement or breakdown of target molecules. For instance, drug researchers can see how a new drug is metabolized as it travels through the test subject's body. To accomplish this,...
What Kind of Fume Hoods Are Available to Today's Labs?
While there are a lot of essential pieces of equipment used in laboratories, fume hoods are one of the most important devices labs have. When lab technicians are working with materials that are classified with health hazards, it's important to work in an area that has a fume hood so the harmful fumes can be...
3 Benefits Cleanrooms Can Offer
With the United States being the number one largest national producer of chemical products in the world, it's no surprise that there is an astounding number of laboratories throughout the country. And whether that laboratory is engaged in Carbon 14 production or pharmaceutical research and development, many laboratory settings contain cleanrooms. In labs, cleanrooms...